Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 20% less
These brands contain the same active ingredient (Secnidazole). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Secnid DS is indicated for:
Pharmacology
Secnidazole is absorbed quickly after it is taken by mouth. Blood levels peak about 3 hours after a 2 gm oral dose. The plasma half-life is around 20 hours, so the drug stays in the body for a long time. Most of it leaves the body through the urine, and about 50% of the dose is passed out within 120 hours. Among the second-generation nitroimidazoles, secnidazole has the longest half-life, and a single 2 gm dose keeps therapeutic blood levels going for 72 hours.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Secnidazole tablets should be taken by mouth. The dosage schedule is as follows.
For acute intestinal amoebiasis, adults may take a single 2 gm dose, preferably just before a meal, while children may take a single dose of 30 mg/kg, also preferably just before a meal.
For asymptomatic amoebiasis, including the minute and cystic forms, adults may take 2 gm once daily for 3 days only, and children may take 30 mg/kg once daily for 3 days only, in both cases preferably just before a meal.
For hepatic amoebiasis, evacuation of pus must be carried out at the same time as Secnidazole treatment during the suppurative stage. Adults may take 1.50 gm per day, either as a single dose or in divided doses, just before a meal, for 5 days, and children may take 30 mg/kg per day in the same manner, just before a meal, for 5 days.
For giardiasis, adults may take a single 2 gm dose, preferably just before a meal, while children may take a single dose of 35 to 50 mg/kg, also preferably just before a meal.
For trichomoniasis, adults may take a single 2 gm dose, preferably just before a meal, and the partner should receive the same treatment at the same time.
Side Effects
D-Zole has generally shown good tolerance in clinical studies, with no serious adverse reactions reported so far. Like other nitroimidazole medicines, it can still cause side effects, though these are rarely serious. Most common: digestive upset, nausea, upper abdominal pain, a metallic taste, and inflammation of the tongue or mouth lining. Occasional: hives and a mild, reversible drop in white blood cell count that resolves once treatment is stopped. Rare: dizziness, unsteady movement and poor muscle coordination, tingling sensations, and nerve damage in the hands or feet. Very rarely, gastrointestinal problems such as nausea, vomiting, and upper abdominal pain have also been reported with D-Zole.
Cautions & Contraindications
Warnings & Precautions
Patients should be told not to drink alcohol while they are being treated with D-Zole, because of the possibility of an antabuse effect. D-Zoleshould be avoided in patients who have a history of blood dyscrasia.
Contraindications
Secnidazole should not be used by patients who are hypersensitive to imidazole derivatives.
Pregnancy & Breastfeeding
Secnidazole may be prescribed in pregnancy, but only after the first trimester. Like other similar drugs, Secnidazole should not be given during the first trimester or while a woman is breastfeeding, because Secnidazole is found in the placenta and in breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Secnidazole in a cool, dry place and away from heat.
Drug Interactions
Common questions about Secnid DS 1000 mg
What is Secnid DS 1000 mg Tablet?
Secnid DS 1000 mg Tablet is a medicine that contains Secnidazole. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Amoebicides group of medicines.
What is Secnid DS used for?
Secnid DS is used for: Amoebiasis, Giardiasis.
What are the side effects of Secnid DS?
D-Zole has generally shown good tolerance in clinical studies, with no serious adverse reactions reported so far. Like other nitroimidazole medicines, it can still cause side effects, though these are rarely serious.
Can I take Secnid DS during pregnancy or while breastfeeding?
Secnidazole may be prescribed in pregnancy, but only after the first trimester. Like other similar drugs, Secnidazole should not be given during the first trimester or while a woman is breastfeeding, because Secnidazole is found in the placenta and in breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Secnid DS?
Keep Secnidazole in a cool, dry place and away from heat.
Can I take other medicines with Secnid DS?
Some medicines can interact with Secnidazole, for example: Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Secnizol DS by Incepta Pharmaceuticals Ltd. has the same ingredient and strength for ৳16.00 per unit, compared with ৳20.06 for Secnid DS. Ask your doctor or pharmacist before switching.
Do I need a prescription for Secnid DS?
Secnid DS is a prescription (Rx) medicine. Take it as your doctor advises.