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These brands contain the same active ingredient (Secnidazole). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Secnid DS is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Secnidazole tablets should be taken by mouth. The dosage schedule is as follows. For acute intestinal amoebiasis, adults may take a single 2 gm dose, preferably just before a meal, while children may take a single dose of 30 mg/kg, also preferably just before a meal. For asymptomatic amoebiasis, including the minute and cystic forms, adults may take 2 gm once daily for 3 days only, and children may take 30 mg/kg once daily for 3 days only, in both cases preferably just before a meal. For hepatic amoebiasis, evacuation of pus must be carried out at the same time as Secnidazole treatment during the suppurative stage. Adults may take 1.50 gm per day, either as a single dose or in divided doses, just before a meal, for 5 days, and children may take 30 mg/kg per day in the same manner, just before a meal, for 5 days. For giardiasis, adults may take a single 2 gm dose, preferably just before a meal, while children may take a single dose of 35 to 50 mg/kg, also preferably just before a meal. For trichomoniasis, adults may take a single 2 gm dose, preferably just before a meal, and the partner should receive the same treatment at the same time.
Side Effects
D-Zole has generally shown good tolerance in clinical studies, with no serious adverse reactions reported so far. Like other nitroimidazole medicines, it can still cause side effects, though these are rarely serious. Most common: digestive upset, nausea, upper abdominal pain, a metallic taste, and inflammation of the tongue or mouth lining. Occasional: hives and a mild, reversible drop in white blood cell count that resolves once treatment is stopped. Rare: dizziness, unsteady movement and poor muscle coordination, tingling sensations, and nerve damage in the hands or feet. Very rarely, gastrointestinal problems such as nausea, vomiting, and upper abdominal pain have also been reported with D-Zole.
Cautions & Contraindications
Warnings & Precautions
Patients should be advised not to take alcohol during treatment with D-Zole (because of the possibility of antabuse effect). Administration of D-Zoleshould be avoided to patients with a history of blood dyscrasia.
Contraindications
Secnidazole should not be used by patients who are hypersensitive to imidazole derivatives.