More from Secnidal
Other strengths and forms by Synovia Pharma PLC.
Indications & Uses
Secnidal is indicated for:
Pharmacology
Secnidazole is absorbed quickly after it is taken by mouth. Blood levels peak about 3 hours after a 2 gm oral dose. The plasma half-life is around 20 hours, so the drug stays in the body for a long time. Most of it leaves the body through the urine, and about 50% of the dose is passed out within 120 hours. Among the second-generation nitroimidazoles, secnidazole has the longest half-life, and a single 2 gm dose keeps therapeutic blood levels going for 72 hours.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Secnidazole tablets should be taken by mouth. The dosage schedule is as follows.
For acute intestinal amoebiasis, adults may take a single 2 gm dose, preferably just before a meal, while children may take a single dose of 30 mg/kg, also preferably just before a meal.
For asymptomatic amoebiasis, including the minute and cystic forms, adults may take 2 gm once daily for 3 days only, and children may take 30 mg/kg once daily for 3 days only, in both cases preferably just before a meal.
For hepatic amoebiasis, evacuation of pus must be carried out at the same time as Secnidazole treatment during the suppurative stage. Adults may take 1.50 gm per day, either as a single dose or in divided doses, just before a meal, for 5 days, and children may take 30 mg/kg per day in the same manner, just before a meal, for 5 days.
For giardiasis, adults may take a single 2 gm dose, preferably just before a meal, while children may take a single dose of 35 to 50 mg/kg, also preferably just before a meal.
For trichomoniasis, adults may take a single 2 gm dose, preferably just before a meal, and the partner should receive the same treatment at the same time.
Side Effects
D-Zole has generally shown good tolerance in clinical studies, with no serious adverse reactions reported so far. Like other nitroimidazole medicines, it can still cause side effects, though these are rarely serious. Most common: digestive upset, nausea, upper abdominal pain, a metallic taste, and inflammation of the tongue or mouth lining. Occasional: hives and a mild, reversible drop in white blood cell count that resolves once treatment is stopped. Rare: dizziness, unsteady movement and poor muscle coordination, tingling sensations, and nerve damage in the hands or feet. Very rarely, gastrointestinal problems such as nausea, vomiting, and upper abdominal pain have also been reported with D-Zole.
Cautions & Contraindications
Warnings & Precautions
Patients should be told not to drink alcohol while they are being treated with D-Zole, because of the possibility of an antabuse effect. D-Zoleshould be avoided in patients who have a history of blood dyscrasia.
Contraindications
Secnidazole should not be used by patients who are hypersensitive to imidazole derivatives.
Pregnancy & Breastfeeding
Secnidazole may be prescribed in pregnancy, but only after the first trimester. Like other similar drugs, Secnidazole should not be given during the first trimester or while a woman is breastfeeding, because Secnidazole is found in the placenta and in breast milk.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Secnidazole in a cool, dry place and away from heat.
Drug Interactions
Common questions about Secnidal 750 mg
What is Secnidal 750 mg Suspension?
Secnidal 750 mg Suspension is a medicine that contains Secnidazole. It is made by Synovia Pharma PLC. It belongs to the Amoebicides group of medicines.
What is Secnidal used for?
Secnidal is used for: Amoebiasis, Giardiasis.
What are the side effects of Secnidal?
D-Zole has generally shown good tolerance in clinical studies, with no serious adverse reactions reported so far. Like other nitroimidazole medicines, it can still cause side effects, though these are rarely serious.
Can I take Secnidal during pregnancy or while breastfeeding?
Secnidazole may be prescribed in pregnancy, but only after the first trimester. Like other similar drugs, Secnidazole should not be given during the first trimester or while a woman is breastfeeding, because Secnidazole is found in the placenta and in breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Secnidal?
Keep Secnidazole in a cool, dry place and away from heat.
Can I take other medicines with Secnidal?
Some medicines can interact with Secnidazole, for example: Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Secnidal?
Secnidal is a prescription (Rx) medicine. Take it as your doctor advises.