Indications
Z-Lidocaine Jelly is used for surface anaesthesia of the male and female urethra, for the topical treatment of painful urethritis, as an anaesthetic lubricant for endotracheal intubation, and to provide adequate analgesia during endoscopy.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Lidocaine works mainly by blocking the entry of sodium into nerve cells through channels in the cell membrane known as voltage gated sodium channels. When this sodium entry is blocked, the nerve cannot generate an action potential, so the signal is not carried forward. The site it binds to is thought to lie on the inner, cytoplasmic side of the sodium channel. Because lidocaine attaches more readily to sodium channels that are in their activated state, it blocks nerves that are firing rapidly more quickly than those that are not; this is known as state dependent blockade.
Pregnancy & Breastfeeding
During pregnancy, there isn't enough reliable evidence to say for certain that lidocaine hydrochloride is safe, though it has been used widely for many years without apparent problems. If treatment is needed during pregnancy, it may be used when no safer option is available. Lidocaine does pass into breast milk, but only in amounts small enough that it generally poses no risk to a nursing child at the doses used for treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.