শুধুমাত্র তথ্যমূলক — চিকিৎসা পরামর্শ নয়। সর্বদা লাইসেন্সপ্রাপ্ত স্বাস্থ্যসেবা প্রদানকারীর পরামর্শ নিন।

MedBD
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Community data Updated 2 মাস আগে

ইঙ্গিত

Z-Lidocaine Jelly is used for surface anaesthesia of the male and female urethra, for the topical treatment of painful urethritis, as an anaesthetic lubricant for endotracheal intubation, and to provide adequate analgesia during endoscopy.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Lidocaine works mainly by blocking the entry of sodium into nerve cells through channels in the cell membrane known as voltage gated sodium channels. When this sodium entry is blocked, the nerve cannot generate an action potential, so the signal is not carried forward. The site it binds to is thought to lie on the inner, cytoplasmic side of the sodium channel. Because lidocaine attaches more readily to sodium channels that are in their activated state, it blocks nerves that are firing rapidly more quickly than those that are not; this is known as state dependent blockade.

Pregnancy & Breastfeeding

During pregnancy, there isn't enough reliable evidence to say for certain that lidocaine hydrochloride is safe, though it has been used widely for many years without apparent problems. If treatment is needed during pregnancy, it may be used when no safer option is available. Lidocaine does pass into breast milk, but only in amounts small enough that it generally poses no risk to a nursing child at the doses used for treatment.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Urethral anaesthesia: For surface anaesthesia of the adult male urethra, 400 mg is required to achieve adequate analgesia. For surface anaesthesia of the adult female urethra, instil 100 to 200 mg in small portions to fill the whole urethra. To obtain adequate anaesthesia, allow several minutes before performing the urological procedure. Lubrication for endotracheal intubation: Apply 100 mg to the surface of the tube just before insertion. Take care to avoid introducing the product into the lumen of the tube. Endoscopy: Instillation of 200 to 400 mg is recommended for adequate analgesia, and a small amount should be applied to the instrument for lubrication. Debilitated patients, elderly patients and children should be given doses in keeping with their age and physical condition. Note: The applicator is sterilised for 5 minutes in boiling water, cooled and attached to the tube. The jelly is instilled slowly as required. The applicator should be detached after each use and the tube kept tightly closed.

পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া

পার্শ্বপ্রতিক্রিয়া

No side-effect data recorded yet.

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