Indications
Doxophylline (DFN) is used to relieve bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and other pulmonary conditions involving spasm of the bronchial airways.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Doxophylline is a newer type of bronchodilator. Its structure differs from Theophylline's by the presence of a dioxolane group at position 7. It works by selectively blocking the phosphodiesterase 4 enzyme, which relaxes the smooth muscle lining the airways. Unlike Theophylline, however, Doxophylline binds much less strongly to adenosine A1 and A2 receptors, and this is thought to be why it tends to be better tolerated. It has also been shown to suppress platelet-activating factor (PAF) and reduce the production of leukotrienes.
Pregnancy & Breastfeeding
Pregnancy and Lactation: Animal tests have shown that the active ingredient of Doxophylline does not interfere with pre and postnatal growth. However, as there is not sufficient clinical evidence about the effects of the drug during pregnancy, use of the drug during pregnancy should be evaluated carefully case by case on the basis of the risk-benefit ratio. The drug is contraindicated during lactation.Effects on ability to drive and use machines: The product does not affect the patient's alertness and therefore does not interfere with his/her ability to drive and use machines.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.