Indications
T-Drop is a topical antibiotic used to treat external bacterial infections of the eye caused by susceptible organisms. These include Gram-positive bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and Streptococcus spp. of group A beta-hemolytic and some nonhemolytic species; and Gram-negative bacteria such as E. coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Klebsiella spp., Proteus mirabilis (Proteusmirabillis), Proteus vulgaris, Haemophilus influenzae, Morganella morganii, Acinetobacter calcoaceticus, Providentia, Serratia, Salmonella spp., and some strains of Neisseria.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Like other aminoglycosides, Tobramycin's bactericidal activity depends on active transport into sensitive bacterial cells. Once inside the cell, Tobramycin binds to the 30S subunit, and to some extent the 50S subunit, of the bacterial ribosome, inhibiting protein synthesis and causing errors in the transcription of the genetic code. Exactly how this leads to cell death is not fully understood, and other mechanisms, including effects on membrane permeability, may also play a role.
Pregnancy & Breastfeeding
Tobramycin has been placed in Pregnancy Category B, but that does not mean it has been proven safe. There are no adequate and well-controlled studies in pregnant women. So it should be used during pregnancy only when the likely benefit to the mother outweighs the possible risk to the unborn baby. Your doctor will weigh this with you.
Tobramycin may pass into human milk. If you are breastfeeding and need this medicine, you and your doctor should decide whether to stop nursing or to stop the drug.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.