Indications
T-Drop is a topical antibiotic used to treat external bacterial infections of the eye caused by susceptible organisms. These include Gram-positive bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and Streptococcus spp. of group A beta-hemolytic and some nonhemolytic species; and Gram-negative bacteria such as E. coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Klebsiella spp., Proteus mirabilis (Proteusmirabillis), Proteus vulgaris, Haemophilus influenzae, Morganella morganii, Acinetobacter calcoaceticus, Providentia, Serratia, Salmonella spp., and some strains of Neisseria.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Like other aminoglycosides, Tobramycin's bactericidal activity depends on active transport into sensitive bacterial cells. Once inside the cell, Tobramycin binds to the 30S subunit, and to some extent the 50S subunit, of the bacterial ribosome, inhibiting protein synthesis and causing errors in the transcription of the genetic code. Exactly how this leads to cell death is not fully understood, and other mechanisms, including effects on membrane permeability, may also play a role.
Pregnancy & Breastfeeding
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. This drug should only be used during pregnancy, if the potential benefits outweigh the possible risk to the fetus. Drug may excreted into human milk. A decision should be made whether to discontinue nursing or to taking the drug.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.