Indications & Uses
Bacide is indicated for:
Pharmacology
Like other aminoglycosides, Tobramycin's bactericidal activity depends on active transport into sensitive bacterial cells. Once inside the cell, Tobramycin binds to the 30S subunit, and to some extent the 50S subunit, of the bacterial ribosome, inhibiting protein synthesis and causing errors in the transcription of the genetic code. Exactly how this leads to cell death is not fully understood, and other mechanisms, including effects on membrane permeability, may also play a role.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
For mild to moderate infections, apply a small amount into the conjunctival sac of the affected eye or eyes 2 to 3 times daily. For severe infections, apply a small amount 3 to 4 times daily until improvement is obtained, then reduce the dose gradually.
For mild to moderate infections, instill 1 or 2 drops into the affected eye or eyes every 4 hours. For severe infections, instill 2 drops into the affected eye or eyes every hour until improvement is observed.
Pediatric use: Safety and effectiveness in children under 1 year of age have not been established.
Side Effects
The most common side effects of T-Drop ophthalmic solution are localised irritation of the eye, redness of the conjunctiva, and hypersensitivity reactions such as itching and swelling of the eyelids.
Cautions & Contraindications
Warnings & Precautions
Some patients may develop mild sensitivity to aminoglycosides applied topically. If a sensitivity reaction occurs, stop using the medicine. Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.
Contraindications
Tobramycin should not be used in patients who are known to be hypersensitive to tobramycin or to any other ingredient in the preparation.
Pregnancy & Breastfeeding
Tobramycin has been placed in Pregnancy Category B, but that does not mean it has been proven safe. There are no adequate and well-controlled studies in pregnant women. So it should be used during pregnancy only when the likely benefit to the mother outweighs the possible risk to the unborn baby. Your doctor will weigh this with you.
Tobramycin may pass into human milk. If you are breastfeeding and need this medicine, you and your doctor should decide whether to stop nursing or to stop the drug.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If you take too much tobramycin, the signs and symptoms can look much like the side effects described above.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Tobramycin away from light and store it in a cool, dry place, below 25°C. Keep it out of the reach of children. Once the bottle has been opened, use it within 4 weeks.
Drug Interactions
Common questions about Bacide 3 mg/ml
What is Bacide 3 mg/ml Eye Drops?
Bacide 3 mg/ml Eye Drops is a medicine that contains Tobramycin. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Aminoglycosides group of medicines.
What is Bacide used for?
Bacide is used for: Bacterial Infection.
What are the side effects of Bacide?
The most common side effects of T-Drop ophthalmic solution are localised irritation of the eye, redness of the conjunctiva, and hypersensitivity reactions such as itching and swelling of the eyelids.
Can I take Bacide during pregnancy or while breastfeeding?
Tobramycin has been placed in Pregnancy Category B, but that does not mean it has been proven safe. There are no adequate and well-controlled studies in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Bacide?
If you take too much tobramycin, the signs and symptoms can look much like the side effects described above. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Bacide?
Keep Tobramycin away from light and store it in a cool, dry place, below 25°C. Keep it out of the reach of children.
Can I take other medicines with Bacide?
Some medicines can interact with Tobramycin, for example: Polymyxin B Sulfate, Piperacillin + Tazobactam, Triamcinolone + Neomycin + Nystatin + Gramicidin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Bacide?
Bacide is a prescription (Rx) medicine. Take it as your doctor advises.