Propantheline Bromide
Indications
Propa is used in the treatment of the following conditions. It serves as adjunctive therapy in the treatment of peptic ulcer (gastric and duodenal). It provides relief of the symptoms of gastritis (stomach upset, gastrointestinal bleeding, blood in vomit, blood in stool, persistent pain). It is used for the symptomatic treatment of diarrhoea related irritable bowel syndrome (irritable colon, spastic colon, acute enterocolitis, functional GI disorders etc). It is also used for urinary incontinence and for the control of salivation and enuresis. It improves lactose intolerance and prevents excessive sweating (hyperhidrosis).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Propantheline Bromide works in two ways. First, it acts as an anticholinergic, which means it blocks the receptors that acetylcholine normally binds to, so it reduces the effect of acetylcholine. Acetylcholine is a chemical released from nerves that tells muscles to contract. Second, it has a direct relaxing effect on smooth muscle. This is why it is classed as an antimuscarinic with antispasmodic properties.
By blocking acetylcholine, Propantheline slows down movement in the gut and reduces the amount of stomach acid produced. It also helps control excessive secretions from the throat, windpipe and airways. Secretions from the pancreas, along with sweat and saliva, are reduced as well.
Pregnancy & Breastfeeding
Propantheline bromide falls under pregnancy category C. No animal reproduction studies have been carried out with this drug, so it should only be used during pregnancy if the need is clearly established. Whether it passes into breast milk is also unknown; since many medicines do pass into breast milk, it should be used with caution in breastfeeding mothers. As with other anticholinergic medicines, it may also reduce milk supply.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.