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Other brands with the same active ingredient
These brands contain the same active ingredient (Propantheline Bromide). Same strength and form. Confirm the switch with your doctor or pharmacist.
Propanthene
Rx15 mg • Tablet
Indications & Uses
Propanthene is indicated for:
Pharmacology
Propantheline Bromide works in two ways. First, it acts as an anticholinergic, which means it blocks the receptors that acetylcholine normally binds to, so it reduces the effect of acetylcholine. Acetylcholine is a chemical released from nerves that tells muscles to contract. Second, it has a direct relaxing effect on smooth muscle. This is why it is classed as an antimuscarinic with antispasmodic properties.
By blocking acetylcholine, Propantheline slows down movement in the gut and reduces the amount of stomach acid produced. It also helps control excessive secretions from the throat, windpipe and airways. Secretions from the pancreas, along with sweat and saliva, are reduced as well.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual starting adult dosage of Propantheline Bromide is 75 mg a day, taken as one tablet (15 mg) 30 minutes before each meal, three times daily, plus two tablets at bedtime. The dosage should then be adjusted according to the patient's individual response and tolerance, but the maximum daily dosage should not exceed 120 mg.
Pediatric use: safety and effectiveness in pediatric patients have not been established.
Side Effects
Side effects of propantheline bromide are usually dose-related and generally clear up once treatment is stopped. Varying degrees of dry mouth, dry skin and dilated pupils (mydriasis) may occur. Other reported side effects include difficulty passing urine (urinary retention), nausea, vomiting, constipation, headache, nervousness and mental confusion.
Cautions & Contraindications
Warnings & Precautions
Propantheline should be used with caution in elderly patients and in anyone with autonomic neuropathy, liver or kidney disease, an overactive thyroid (hyperthyroidism), coronary heart disease, congestive heart failure, a rapid or irregular heartbeat (cardiac tachyarrhythmia), or high blood pressure, because anticholinergic medicines can make these conditions worse.
Contraindications
Propantheline Bromide should not be given to patients with any of the following: Hypersensitivity to Propantheline bromide or other anticholinergic agents; glaucoma; obstructive disease of the gastrointestinal tract (pyloroduodenal stenosis, paralytic ileus etc.); obstructive uropathy (e.g. prostatic hypertrophy); intestinal atony of the elderly; and myasthenia gravis.
Pregnancy & Breastfeeding
Propantheline bromide falls under pregnancy category C. No animal reproduction studies have been carried out with this drug, so it should only be used during pregnancy if the need is clearly established. Whether it passes into breast milk is also unknown; since many medicines do pass into breast milk, it should be used with caution in breastfeeding mothers. As with other anticholinergic medicines, it may also reduce milk supply.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In an overdose of Propantheline Bromide, the usual side effects get stronger, starting with nausea and vomiting. After that come CNS disturbances, which range from restlessness and excitement to psychotic behaviour. Circulatory changes follow (flushing, a fall in blood pressure and circulatory failure), and then respiratory failure and paralysis.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Propantheline Bromide at or below 30°C. Keep it away from light, and keep it out of the reach of children.
Drug Interactions
Common questions about Propanthene 15 mg
What is Propanthene 15 mg Tablet?
Propanthene 15 mg Tablet is a medicine that contains Propantheline Bromide. It is made by G. A. Company Ltd. It belongs to the Anticholinergics (antimuscarinics)/ Anti-spasmodics group of medicines.
What is Propanthene used for?
Propanthene is used for: Pain, Peptic Ulcer, Diarrhea, Irritable Bowel Syndrome.
What are the side effects of Propanthene?
Side effects of propantheline bromide are usually dose-related and generally clear up once treatment is stopped. Varying degrees of dry mouth, dry skin and dilated pupils (mydriasis) may occur.
Can I take Propanthene during pregnancy or while breastfeeding?
Propantheline bromide falls under pregnancy category C. No animal reproduction studies have been carried out with this drug, so it should only be used during pregnancy if the need is clearly established. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Propanthene?
In an overdose of Propantheline Bromide, the usual side effects get stronger, starting with nausea and vomiting. After that come CNS disturbances, which range from restlessness and excitement to psychotic behaviour. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Propanthene?
Store Propantheline Bromide at or below 30°C. Keep it away from light, and keep it out of the reach of children.
Can I take other medicines with Propanthene?
Some medicines can interact with Propantheline Bromide, for example: Haloperidol, Digoxin, Levodopa, Ketoconazole. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Propanthene?
Propanthene is a prescription (Rx) medicine. Take it as your doctor advises.