Propafenone Hydrochloride
Indications
Rythmosin is used to treat paroxysmal atrial fibrillation/flutter (PAF) and paroxysmal supraventricular tachycardia (PSVT). It is also used to treat documented ventricular arrhythmias.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Propafenone works by slowing the entry of sodium ions into heart muscle cells, which makes those cells less excitable. It acts more selectively on cells that are firing at a high rate, though it also affects normal heart cells more than class Ia or Ib agents do. Unlike a typical class Ic antiarrhythmic, propafenone also has beta-blocking activity, which can lead to a slowed heart rate (bradycardia) and airway narrowing (bronchospasm).
Pregnancy & Breastfeeding
Pregnancy: The FDA has placed propafenone in pregnancy category C. There are no well-controlled studies in pregnant women. A small amount of limited data shows that propafenone has been given during the third trimester without any harmful effects on the mother or the baby. So it should be used during pregnancy only when the benefit to the mother is greater than the risk.
Breastfeeding: It isn't known whether this medicine passes into human milk. Many medicines do, and propafenone could cause serious side effects in a nursing baby. So the doctor needs to decide whether to stop breastfeeding or stop the medicine, taking into account how important the medicine is for the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.