Propafenone Hydrochloride
Indications
Rythmosin is used to treat paroxysmal atrial fibrillation/flutter (PAF) and paroxysmal supraventricular tachycardia (PSVT). It is also used to treat documented ventricular arrhythmias.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Propafenone works by slowing the entry of sodium ions into heart muscle cells, which makes those cells less excitable. It acts more selectively on cells that are firing at a high rate, though it also affects normal heart cells more than class Ia or Ib agents do. Unlike a typical class Ic antiarrhythmic, propafenone also has beta-blocking activity, which can lead to a slowed heart rate (bradycardia) and airway narrowing (bronchospasm).
Pregnancy & Breastfeeding
Pregnancy: Propafenone has been assigned to pregnancy category C by the FDA. There are no controlled data in human pregnancy. Limited data indicate that propafenone has been administered during the third trimester of pregnancy without adverse maternal or fetal effects. Propafenone should be given during pregnancy only when benefit outweighs risk.Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from propafenone, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.