Indications
Nitrofurantoin (NFT) is specifically indicated for the treatment and prophylaxis of urinary tract infections caused by susceptible strains of Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus and certain susceptible strains of Klebsiella and Enterobacter species.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Nitrofurantoin is an antibacterial agent used specifically for urinary tract infections. It is highly soluble in urine, which it may turn brown. It works by inactivating or altering bacterial ribosomal proteins and other macromolecules. Nitrofurantoin has been shown to be active against the following bacteria: Gram-Positive Aerobes: Staphylococcus saprophyticus, coagulase-negative staphylococci (including Staphylococcus epidermidis), Enterococcus faecalis, Staphylococcus aureus, Streptococcus agalactiae, Group D streptococci, and viridans group streptococci. Gram-Negative Aerobes: Escherichia coli, Citrobacter amalonaticus, Citrobacter diversus, Citrobacter freundii, Klebsiella oxytoca, and Klebsiella ozaenae.
Pregnancy & Breastfeeding
Pregnancy Category B. Well-controlled studies in pregnant women are lacking, so this medicine should be used in pregnancy only if there is a clear need for it. Nitrofurantoin passes into breast milk in trace amounts. Because nursing infants under one month of age may be more susceptible to serious side effects from it, the mother and her doctor should decide together whether to stop breastfeeding or stop the medicine, weighing how important it is for her treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.