Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →More from Nintoin
Other strengths and forms by Incepta Pharmaceuticals Ltd.
Indications & Uses
Nitrofurantoin (NFT) is specifically indicated for the treatment and prophylaxis of urinary tract infections caused by susceptible strains of Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus and certain susceptible strains of Klebsiella and Enterobacter species.
Pharmacology
Nitrofurantoin is an antibacterial agent used specifically for urinary tract infections. It is highly soluble in urine, which it may turn brown. It works by inactivating or altering bacterial ribosomal proteins and other macromolecules. Nitrofurantoin has been shown to be active against the following bacteria: Gram-Positive Aerobes: Staphylococcus saprophyticus, coagulase-negative staphylococci (including Staphylococcus epidermidis), Enterococcus faecalis, Staphylococcus aureus, Streptococcus agalactiae, Group D streptococci, and viridans group streptococci. Gram-Negative Aerobes: Escherichia coli, Citrobacter amalonaticus, Citrobacter diversus, Citrobacter freundii, Klebsiella oxytoca, and Klebsiella ozaenae.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Nitrofurantoin tablets for adults, uncomplicated urinary tract infections: 50 to 100 mg four times a day, and the lower dose is the one recommended. Treatment goes on for one week, or for at least 3 days after the urine has become sterile. If long-term suppressive therapy is needed, cutting the dose to 50 to 100 mg at bedtime may be enough.
Nitrofurantoin capsules for adults, acute uncomplicated urinary tract infections (UTIs): 50 mg four times daily for 7 days. Long-term suppression is 50 to 100 mg once a day. Prophylaxis is 50 mg four times daily during the procedure and for three days afterwards.
Nitrofurantoin SR capsules for adults: one 100 mg capsule every 12 hours for seven days. Genito-urinary surgical prophylaxis uses one capsule twice daily on the day of the procedure and for the next 3 days.
The suspension and its paediatric dosing are not covered here, as this section deals with adults only.
Side Effects
Most people taking nitrofurantoin notice nausea, headache, or gas as the most common side effects. Less commonly, it can cause diarrhea, indigestion, stomach pain, constipation, vomiting, dizziness, or drowsiness.
Cautions & Contraindications
Warnings & Precautions
If you notice signs of a lung reaction, whether sudden, short-term or long-lasting, NFT should be stopped. Don't take antacids that contain magnesium trisilicate while you are on NFT.
Contraindications
Nitrofurantoin should not be used by patients with anuria, oliguria, or significantly reduced kidney function. It is also contraindicated for pregnant women between 38 and 42 weeks of pregnancy, as well as during labor and delivery. Patients known to be hypersensitive to Nitrofurantoin should not take this medicine either.
Pregnancy & Breastfeeding
Pregnancy Category B. Well-controlled studies in pregnant women are lacking, so this medicine should be used in pregnancy only if there is a clear need for it. Nitrofurantoin passes into breast milk in trace amounts. Because nursing infants under one month of age may be more susceptible to serious side effects from it, the mother and her doctor should decide together whether to stop breastfeeding or stop the medicine, weighing how important it is for her treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
A few cases of acute overdose with Nitrofur have been seen, and none caused any specific symptoms apart from vomiting. Inducing vomiting is recommended.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Nitrofurantoin at a temperature no higher than 30°C and away from light. Keep it out of the reach of children.
Drug Interactions
Common questions about Nintoin 25 mg/5 ml
What is Nintoin 25 mg/5 ml Oral Suspension?
Nintoin 25 mg/5 ml Oral Suspension is a medicine that contains Nitrofurantoin. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Systemic Urinary Anti- infective group of medicines.
What is Nintoin used for?
Nitrofurantoin (NFT) is specifically indicated for the treatment and prophylaxis of urinary tract infections caused by susceptible strains of Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus and certain susceptible strains of Klebsiella and Enterobacter species.
What are the side effects of Nintoin?
Most people taking nitrofurantoin notice nausea, headache, or gas as the most common side effects. Less commonly, it can cause diarrhea, indigestion, stomach pain, constipation, vomiting, dizziness, or drowsiness.
Can I take Nintoin during pregnancy or while breastfeeding?
Pregnancy Category B. Well-controlled studies in pregnant women are lacking, so this medicine should be used in pregnancy only if there is a clear need for it. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Nintoin?
A few cases of acute overdose with Nitrofur have been seen, and none caused any specific symptoms apart from vomiting. Inducing vomiting is recommended. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Nintoin?
Store Nitrofurantoin at a temperature no higher than 30°C and away from light. Keep it out of the reach of children.
Can I take other medicines with Nintoin?
Some medicines can interact with Nitrofurantoin, for example: Aluminium Hydroxide + Magnesium Hydroxide + Simethicone, Sulfinpyrazone, Magnesium, Vitamin C [Ascorbic acid], 6s-5-Methyltetrahydrofolate [Bio-Active Folate], Magnesium Oxide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Nintoin?
Nintoin is a prescription (Rx) medicine. Take it as your doctor advises.