Hydrocortisone

Indications

Asthma Allergic Rhinitis Tuberculosis Viral Infection Eczema Psoriasis Anemia Allergy Cancer Edema

Cortinex (hydrocortisone) is used in these conditions: primary or secondary adrenocortical insufficiency, acute adrenocortical insufficiency, shock that does not respond to conventional therapy, congenital adrenal hyperplasia, hypercalcemia associated with cancer, nonsuppurative thyroiditis and rheumatic disorders. It is also used in dermatologic diseases, namely allergic states, severe seborrheic dermatitis, severe psoriasis, pemphigus and severe erythema multiforme. It is used to control severe or incapacitating allergic conditions, which include bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness, seasonal or perennial allergic rhinitis, drug hypersensitivity reactions, urticarial transfusion reactions and acute noninfectious laryngeal edema. Among eye diseases, Cortinex is used in herpes zoster ophthalmicus, iritis, iridocyclitis, chorioretinitis, diffuse posterior uveitis and choroiditis, and optic neuritis. It is also used in gastrointestinal diseases. For lung conditions, it is used in fulminating or disseminated pulmonary tuberculosis, when given together with appropriate antituberculous chemotherapy. It is also used in Loeffler's syndrome and aspiration pneumonitis. In hematologic disorders, it is used in acquired autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura in adults, secondary thrombocytopenia and erythroblastopenia. In neoplastic diseases, it is used in leukemias and lymphomas in adults and in acute leukemia of childhood. Cortinex is also used in edematous states and in acute exacerbations of multiple sclerosis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Hydrocortisone works by blocking the enzyme phospholipase A2, which in turn stops the production of prostaglandins. It also curbs the release of several chemical agents involved in the inflammatory response, and helps regulate the rate at which proteins are built in the body.

Pregnancy & Breastfeeding

Hydrocortisone should be used during pregnancy and breastfeeding only when it is genuinely necessary.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Tablet: The starting dose of Hydrocortisone Tablets can range from 20 mg to 240 mg per day, depending on the condition being treated. Milder cases generally need lower doses, while some patients may require a higher starting dose. This initial dose is maintained or adjusted until the response is satisfactory. If a reasonable trial period does not bring a satisfactory clinical response, the tablets should be stopped and the patient switched to other suitable therapy. Dosage needs vary from patient to patient and must be tailored to the condition being treated and how the patient responds. Once a good response is achieved, the maintenance dose should be found by lowering the initial dose in small steps at suitable intervals, until the smallest dose that still keeps the response adequate is reached. Regular monitoring of the dose is important throughout treatment. If the drug is being stopped after long term use, it should be tapered off gradually rather than stopped suddenly. Injection: Adults: Given by IM injection, slow IV injection, or IV infusion. The starting dose of Hydrocortisone sterile powder is 100 mg to 500 mg, depending on how severe the condition is. This dose may be repeated every 2, 4, or 6 hours, depending on the patient's response and clinical condition. Children: Given by slow IV injection: up to 1 year, 25 mg; 1 to 5 years, 50 mg; 6 to 12 years, 100 mg.

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Indications

Pharmacology

Pregnancy & Breastfeeding

Dosage Reference

Side Effects & Interactions

Side Effects

Key Interactions