More from Cortinex
Other strengths and forms by Ziska Pharmaceuticals Ltd.
Indications & Uses
Cortinex is indicated for:
Pharmacology
Hydrocortisone works by blocking the enzyme phospholipase A2, which in turn stops the production of prostaglandins. It also curbs the release of several chemical agents involved in the inflammatory response, and helps regulate the rate at which proteins are built in the body.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: Given by IM injection, slow IV injection, or IV infusion. The starting dose of Hydrocortisone sterile powder is 100 mg to 500 mg, depending on how severe the condition is. This dose may be repeated every 2, 4, or 6 hours, depending on the patient's response and clinical condition.
Children: Given by slow IV injection: up to 1 year, 25 mg; 1 to 5 years, 50 mg; 6 to 12 years, 100 mg.
Dosage for other forms (1)
The starting dose of Hydrocortisone Tablets can range from 20 mg to 240 mg per day, depending on the condition being treated. Milder cases generally need lower doses, while some patients may require a higher starting dose. This initial dose is maintained or adjusted until the response is satisfactory. If a reasonable trial period does not bring a satisfactory clinical response, the tablets should be stopped and the patient switched to other suitable therapy. Dosage needs vary from patient to patient and must be tailored to the condition being treated and how the patient responds. Once a good response is achieved, the maintenance dose should be found by lowering the initial dose in small steps at suitable intervals, until the smallest dose that still keeps the response adequate is reached. Regular monitoring of the dose is important throughout treatment. If the drug is being stopped after long term use, it should be tapered off gradually rather than stopped suddenly.
Side Effects
Cortinex is generally well tolerated, and problems mainly arise with prolonged use at high doses. In such cases, it may cause cardiac arrhythmia, esophageal candidiasis, and menstrual irregularity. It can also reduce carbohydrate and glucose tolerance, and lead to fluid retention, increased appetite, and weight gain. Some patients experience euphoria, mood swings, depression, or insomnia, and acne can also occur.
Cautions & Contraindications
Warnings & Precautions
Cortinex should be used cautiously in patients with a history of peptic ulcer disease, since it can raise the risk of ulcers recurring. Caution is also advised in those with congestive heart failure, high blood pressure, glaucoma, diabetes mellitus, or epilepsy.
Contraindications
Hydrocortisone should not be used if there is a severe systemic fungal infection or a known allergy to any ingredient in this medicine.
Pregnancy & Breastfeeding
Hydrocortisone should be used during pregnancy and breastfeeding only when it is genuinely necessary.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Hydrocortisone below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Cortinex 100 mg
What is Cortinex 100 mg Injection?
Cortinex 100 mg Injection is a medicine that contains Hydrocortisone. It is made by Ziska Pharmaceuticals Ltd. It belongs to the Glucocorticoids group of medicines.
What is Cortinex used for?
Cortinex is used for: Asthma, Allergic Rhinitis, Tuberculosis, Viral Infection, Eczema, Psoriasis, Anemia, Allergy, Cancer, Edema.
What are the side effects of Cortinex?
Cortinex is generally well tolerated, and problems mainly arise with prolonged use at high doses. In such cases, it may cause cardiac arrhythmia, esophageal candidiasis, and menstrual irregularity.
Can I take Cortinex during pregnancy or while breastfeeding?
Hydrocortisone should be used during pregnancy and breastfeeding only when it is genuinely necessary. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Cortinex?
Store Hydrocortisone below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Cortinex?
Some medicines can interact with Hydrocortisone, for example: Telmisartan + Hydrochlorothiazide, Ketoconazole, Phenytoin, Phenobarbital, Vitamin C [Ascorbic acid], Vitamin C + Vitamin E. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Cortinex?
Cortinex is a prescription (Rx) medicine. Take it as your doctor advises.