Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Cortinex is indicated for use in the following conditions:  Primary or secondary adrenocortical insufficiency Acute adrenocortical insufficiency Shock unresponsive to conventional therapy Congenital adrenal hyperplasia Hypercalcemia associated with cancer ... Read moreCortinex is indicated for use in the following conditions:  Primary or secondary adrenocortical insufficiency Acute adrenocortical insufficiency Shock unresponsive to conventional therapy Congenital adrenal hyperplasia Hypercalcemia associated with cancer Nonsuppurative thyroiditis Rheumatic Disorders Dermatologic Diseases (Allergic States, Severe seborrheic dermatitis, Severe psoriasis, Pemphigus, Severe erythema multiforme) Control of severe or incapacitating allergic conditions (Bronchial asthma, Contact dermatitis, Atopic dermatitis, Serum sickness, Seasonal or perennial allergic rhinitis, Drug hypersensitivity reactions, Urticarial transfusion reactions, Acute noninfectious laryngeal edema) Ophthalmic Diseases (Herpes zoster ophthalmicus, Iritis, iridocyclitis, Chorioretinitis, Diffuse posterior uveitis and choroiditis, Optic neuritis) Gastrointestinal Diseases Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy Loeffler's syndrome Aspiration pneumonitis Hematologic Disorders (Acquired, autoimmune hemolytic anemia, Idiopathic thrombocytopenic purpura in adults, Secondary thrombocytopenia, Erythroblastopenia) Neoplastic Diseases (Leukemias and lymphomas in adults, Acute leukemia of childhood) Edematous States Acute exacerbations of multiple sclerosis

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Hydrocortisone works by blocking the enzyme phospholipase A2, which in turn stops the production of prostaglandins. It also curbs the release of several chemical agents involved in the inflammatory response, and helps regulate the rate at which proteins are built in the body.

Pregnancy & Breastfeeding

Hydrocortisone should be used during pregnancy and breastfeeding only when it is genuinely necessary.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Tablet: The starting dose of Hydrocortisone Tablets can range from 20 mg to 240 mg per day, depending on the condition being treated. Milder cases generally need lower doses, while some patients may require a higher starting dose. This initial dose is maintained or adjusted until the response is satisfactory. If a reasonable trial period does not bring a satisfactory clinical response, the tablets should be stopped and the patient switched to other suitable therapy. Dosage needs vary from patient to patient and must be tailored to the condition being treated and how the patient responds. Once a good response is achieved, the maintenance dose should be found by lowering the initial dose in small steps at suitable intervals, until the smallest dose that still keeps the response adequate is reached. Regular monitoring of the dose is important throughout treatment. If the drug is being stopped after long term use, it should be tapered off gradually rather than stopped suddenly. Injection: Adults: Given by IM injection, slow IV injection, or IV infusion. The starting dose of Hydrocortisone sterile powder is 100 mg to 500 mg, depending on how severe the condition is. This dose may be repeated every 2, 4, or 6 hours, depending on the patient's response and clinical condition. Children: Given by slow IV injection: up to 1 year, 25 mg; 1 to 5 years, 50 mg; 6 to 12 years, 100 mg.

Side Effects & Interactions