Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Novelip is indicated for:
Pharmacology
Bempedoic Acid is an adenosine triphosphate-citrate lyase (ACL) inhibitor. It lowers low-density lipoprotein cholesterol (LDL-C) by blocking cholesterol synthesis in the liver. ACL is an enzyme that works upstream of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase in the cholesterol biosynthesis pathway.
Bempedoic acid and its active metabolite, ESP15228, both need to be activated with coenzyme A (CoA) by very long-chain acyl-CoA synthetase 1 (ACSVL1). This turns them into ETC-1002-CoA and ESP15228-CoA, respectively. ACSVL1 is found mainly in the liver. When ETC-1002-CoA inhibits ACL, less cholesterol is made in the liver, and LDL-C in the blood falls because more low-density lipoprotein receptors are produced (upregulation).
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Take Bempedoic Acid 180 mg by mouth once a day, with or without food.
Side Effects
Upper respiratory tract infection, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, pain in extremity, anemia, elevated liver enzymes.
Cautions & Contraindications
Warnings & Precautions
Bempedoic Acid can raise serum uric acid, and this has been seen in patients. Uric acid levels should be checked from time to time as the clinical situation requires. Watch for signs and symptoms of hyperuricemia, and start a urate-lowering drug if it is appropriate. Tendon rupture has also occurred. If the first sign of a tendon rupture appears, stop Bempedoic Acid. Patients who have had a tendon disorder or a tendon rupture in the past should avoid it.
Drug Interactions
Common questions about Novelip 180 mg
What is Novelip 180 mg Tablet?
Novelip 180 mg Tablet is a medicine that contains Bempedoic Acid. It is made by Renata PLC.
What is Novelip used for?
Novelip is used for: Hyperlipidemia.
What are the side effects of Novelip?
Upper respiratory tract infection, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, pain in extremity, anemia, elevated liver enzymes.
Can I take other medicines with Novelip?
Some medicines can interact with Bempedoic Acid, for example: Simvastatin, Bempedoic Acid + Ezetimibe, Pravastatin Sodium. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Novelip is already among the lowest-priced brands of Bempedoic Acid at this strength.
Do I need a prescription for Novelip?
Novelip is a prescription (Rx) medicine. Take it as your doctor advises.