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Other brands with the same active ingredient
These brands contain the same active ingredient (Bempedoic Acid). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Bemvas 180 is indicated for:
Pharmacology
Bempedoic Acid is an adenosine triphosphate-citrate lyase (ACL) inhibitor. It lowers low-density lipoprotein cholesterol (LDL-C) by blocking cholesterol synthesis in the liver. ACL is an enzyme that works upstream of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase in the cholesterol biosynthesis pathway.
Bempedoic acid and its active metabolite, ESP15228, both need to be activated with coenzyme A (CoA) by very long-chain acyl-CoA synthetase 1 (ACSVL1). This turns them into ETC-1002-CoA and ESP15228-CoA, respectively. ACSVL1 is found mainly in the liver. When ETC-1002-CoA inhibits ACL, less cholesterol is made in the liver, and LDL-C in the blood falls because more low-density lipoprotein receptors are produced (upregulation).
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Take Bempedoic Acid 180 mg by mouth once a day, with or without food.
Side Effects
Upper respiratory tract infection, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, pain in extremity, anemia, elevated liver enzymes.
Cautions & Contraindications
Warnings & Precautions
Bempedoic Acid can raise serum uric acid, and this has been seen in patients. Uric acid levels should be checked from time to time as the clinical situation requires. Watch for signs and symptoms of hyperuricemia, and start a urate-lowering drug if it is appropriate. Tendon rupture has also occurred. If the first sign of a tendon rupture appears, stop Bempedoic Acid. Patients who have had a tendon disorder or a tendon rupture in the past should avoid it.
Pregnancy & Breastfeeding
If pregnancy is recognised while a woman is taking Bempedoic Acid, the medicine should be stopped, unless the benefits of treatment outweigh the possible risks to the baby. There are no data on the use of Bempedoic Acid in pregnant women, so it isn't known whether the medicine raises the risk of major birth defects, miscarriage, or other harmful outcomes for the mother or the baby.
Nothing is known about whether Bempedoic Acid passes into human or animal milk, what effect it has on a breastfed infant, or whether it changes milk production. Breastfeeding is not recommended during treatment with Bempedoic Acid.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Bempedoic Acid below 30ºC. Store it away from light and from damp places. Keep it out of reach of children.
Drug Interactions
Common questions about Bemvas 180 180 mg
What is Bemvas 180 180 mg Tablet?
Bemvas 180 180 mg Tablet is a medicine that contains Bempedoic Acid. It is made by Opsonin Pharma Limited.
What is Bemvas 180 used for?
Bemvas 180 is used for: Hyperlipidemia.
What are the side effects of Bemvas 180?
Upper respiratory tract infection, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, pain in extremity, anemia, elevated liver enzymes.
Can I take Bemvas 180 during pregnancy or while breastfeeding?
If pregnancy is recognised while a woman is taking Bempedoic Acid, the medicine should be stopped, unless the benefits of treatment outweigh the possible risks to the baby. There are no data on the use of Bempedoic Acid in pregnant women, so it isn't known whether the medicine raises the risk of major birth defects, miscarriage, or other harmful outcomes for the mother or the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Bemvas 180?
Keep Bempedoic Acid below 30ºC. Store it away from light and from damp places.
Can I take other medicines with Bemvas 180?
Some medicines can interact with Bempedoic Acid, for example: Simvastatin, Bempedoic Acid + Ezetimibe, Pravastatin Sodium. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Bemvas 180?
Bemvas 180 is a prescription (Rx) medicine. Take it as your doctor advises.