Gadodiamide

Adults: No special preparation of the patient is required. Gadodiamide should be drawn into the syringe immediately before use. The vial is intended for one patient only. Any contrast medium not used in one examination must be discarded. Dosage for adults and children: The recommended dose is 0.1 mmol per kg body weight (equivalent to 0.2 ml per kg body weight) up to 100 kg. For patients above 100 kg body weight, 20 ml is usually enough to provide diagnostically adequate contrast. The required dose should be given as a single intravenous injection. To make sure the contrast medium is completely injected, the intravenous line may be flushed with 5 ml of 0.9% sodium chloride injection. Adults only: When brain metastases are suspected, a dose of 0.3 mmol per kg body weight (equivalent to 0.6 ml per kg body weight) can be given up to 100 kg. Above 100 kg body weight, a total of 60 ml is usually sufficient. This 0.3 mmol per kg dose can be given as a bolus intravenous injection. In patients whose scans remain unclear after the 0.1 mmol per kg injection, a second bolus injection of 0.2 mmol per kg body weight (equivalent to 0.4 ml per kg body weight) may add diagnostic value if given within 20 minutes of the first injection.