ইঙ্গিত ও ব্যবহার
Neuroradiology: Lumbar myelography and thoraco-cervical myelography. Angiography: Used for cerebral angiography, selective coronary angiography, left ventriculography, aortography, angiocardiography, selective visceral arteriography, peripheral arteriography, digital subtraction angiography, venography, and urography. Other diagnostic procedures: Also used for contrast enhancement in CT scanning, as well as arthrography and fistulography.
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
Adults:
Dosage Adults: In neurology, for lumbar myelography and thoraco-cervical myelography, Iopamidol 370 is given at 6 to 13 ml. For urography, Iopamidol 370 is given at 40 to 80 ml, or IV up to 1.5 ml/kg in severe renal disease. Children: The usual dose is 1 to 2.5 ml/kg. Other diagnostic procedures: For contrast enhancement in CT scanning, Iopamidol 370 is given at 0.5 to 2.0 ml/kg. Angiography: For cerebral angiography, Iopamidol 370 is given at 6 to 13 ml. For selective coronary arteriography, 4 to 8 ml per artery. For peripheral arteriography, 20 to 50 ml. For venography, 24 to 60 ml. For angiocardiography, 30 to 80 ml. For left ventriculography, 30 to 80 ml. For percutaneous transfemoral or renal arteriography, 30 ml. For selective renal arteriography, 5 to 10 ml. For hepatic angiography, 70 ml. For coeliac angiography, 40 to 70 ml. For superior mesenteric angiography, 25 to 50 ml. For inferior mesenteric angiography, 5 to 30 ml. For digital subtraction angiography, 30 to 50 ml (10 to 20 ml per second) of Iopamidol 370 is given IV; for cardiac imaging, 25 ml is given for the left ventricle and 2 to 5 ml for the coronary arteries, at 15 ml per second, of Iopamidol 370 given intra-arterially.
পার্শ্বপ্রতিক্রিয়া
The use of organic Iodine compounds may cause untoward side effects and manifestations of anaphylaxis. The symptoms include nausea, vomiting, widespread erythema, generalized heat sensation, headache, coryza, fever, sweating, asthenia, dizziness, pallor, dyspnea, and moderate hypotension. Skin reactions occur in the form of various types of rash or diffuse blister formation. More severe reactions involving the cardiovascular system such as peripheral vasodilation with pronounced hypotension, tachycardia, dyspnea, agitation, cyanosis and loss of consciousness, may require emergency treatment. During intracardiac and /or coronary arteriography, ventricular arrhythmia may infrequently occur. Hyperthyroidism may recur in patients previously treated for graves disease.
সতর্কতা ও নিষেধাজ্ঞা
Warnings & Precautions
Amidol 370/300 should not be drawn into the syringe until immediately before it is used, and once the bottle has been opened it must be used at once. Because of the possibility of serious side effects, organoiodinate contrast media should be used only where there is a genuine need for a radiographic contrast examination, and this should be judged against the patient's clinical status, particularly with regard to any disease of the cardiovascular, urinary, or hepatobiliary system. Contrast media intended for cardioangiography in particular should be used only in hospitals or clinics equipped and staffed to handle intensive-care emergencies. For other diagnostic procedures that call for an iodinated contrast medium, the facility should have resuscitation equipment and emergency treatment on hand at all times. When examining small children or babies, fluid intake should not be restricted before a hypertonic contrast solution is given, and any existing water or electrolyte imbalance should be corrected beforehand. Where possible, X-ray examinations in women should also be carried out during the pre-ovulation phase of the menstrual cycle. For patients due to have a thyroid examination with a radioactive iodine tracer, it should be kept in mind that iodine uptake by the thyroid gland will be reduced for several days, and for up to two weeks, after a dose of an iodinated contrast medium that is cleared through the kidneys. Biguanide oral anti-diabetic agents, such as metformin, are excreted unchanged by the kidneys and so compete with contrast media for renal excretion, which can lead to a reduction in kidney function. Patients with NIDDM (non-insulin-dependent diabetes mellitus) who are taking metformin or another biguanide should therefore be told not to take the drug for 48 hours before and 48 hours after the X-ray examination.
নিষেধাজ্ঞা
There are no absolute contraindications for the use of Amidol, with the possible exception of Waldenström's macroglobulinemia, multiple myeloma, and severe liver or kidney disease.