Sunitix Sunitinib Nelfinavir
ModerateNelfinavir is a strong CYP3A4 inhibitor. That means it slows down the CYP3A4 enzyme family, which the body uses to break down Sunitinib. If you take the two together, Sunitinib can build up and reach higher levels in your blood. Other strong CYP3A4 inhibitors named in the leaflet include Ketoconazole, Itraconazole, Clarithromycin, Atazanavir, Indinavir, Nefazodone, Ritonavir, Saquinavir, Telithromycin and Voriconazole.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.