Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago
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Indications

Avifix contains Nelfinavir and is used to treat HIV infection in patients for whom antiretroviral therapy is appropriate.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Nelfinavir works by selectively and reversibly blocking HIV-1 protease, an enzyme the virus needs to cut its gag-pol polyprotein into functional pieces. By competing for this enzyme, it stops that cleavage step, so the virus particles that are produced are unable to infect new cells.

Pregnancy & Breastfeeding

Pregnancy Category B. No adequate, well-controlled studies have been conducted in pregnant women.

Lactation: The US Public Health Service Centers for Disease Control and Prevention advises HIV-infected mothers not to breast-feed, so as to avoid transmitting HIV to the child after birth.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: For adults, the recommended dose is 1250 mg (five 250 mg tablets) twice daily, or alternatively 750 mg (three 250 mg tablets) three times daily. Nelfinavir should be taken with a meal. Its antiviral activity is enhanced when it is given together with nucleoside analogues, so it is recommended that Nelfinavir be used in combination with nucleoside analogues. For paediatric patients aged 2 to 13 years, the recommended oral dose of Nelfinavir is 20 to 30 mg/kg per dose, given three times daily with a meal.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.