Sizaject Injection Phenytoin Sodium Clozapine
ModeratePhenytoin Sodium can lower the levels and effects of Clozapine in your body, so Clozapine may not work as well as it should. The same thing happens with ciclosporin, tacrolimus and other medicines that are broken down by the CYP2B6 enzyme in the liver.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.