Kinexa 2.5 Rivaroxaban Erythromycin
MajorTaking Rivaroxaban with Erythromycin (a combined P-gp and CYP3A4 inhibitor) increases Rivaroxaban levels and its blood-thinning effects, such as factor Xa inhibition and PT prolongation, so this combination should be avoided.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.