Sunitix 12.5 Sunitinib Rifampicin
ModerateCYP3A4 Inducers: CYP3A4 inducers such as Rifampin may decrease Sutib plasma concentrations. Concurrent administration of Sutinib with the strong CYP3A4 inducer, Rifampin, resulted in a 23% and 46% reduction in the combined (Sutib + primary active metabolite) Cmax and AUC0-∞ values, respectively, after a single dose of Sutinib in healthy volunteers.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.