Geficent Gefitinib Rifampicin
ModerateRifampicin is a strong CYP3A4 inducer, meaning it speeds up how quickly the body breaks down Gefitinib. This can lower the amount of Gefitinib in the blood. In patients taking Gefitinib (Genib) with rifampicin, the Gefitinib dose should be raised from 250 mg to 500 mg daily. Once rifampicin is stopped, wait 7 days and then go back to 250 mg daily.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.