Nibaron Aspirin Diclofenac Sodium + Misoprostol
MajorTaking diclofenac sodium with misoprostol alongside aspirin is not recommended. Aspirin displaces diclofenac sodium from its binding sites, and this leads to lower plasma concentrations, peak plasma levels and AUC values.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.