Indications
Ultrafen Plus is used to relieve the signs and symptoms of osteoarthritis or rheumatoid arthritis in patients who are at high risk of developing NSAID-induced gastric and duodenal ulcers and their complications.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
It is a combination product containing Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties, and Misoprostol, a gastrointestinal (GI) mucosal protective prostaglandin E1 analog. Like other NSAIDs, the exact mechanism of action of Diclofenac Sodium is not completely understood, but it may be related to inhibition of prostaglandin synthetase. NSAIDs inhibit prostaglandin synthesis, and a deficiency of prostaglandins within the gastric and duodenal mucosa may reduce bicarbonate and mucosal secretion, contributing to the mucosal damage caused by NSAIDs. Misoprostol helps counter this GI effect by increasing bicarbonate and mucous production, thereby helping to prevent gastric and duodenal ulcers.
Pregnancy & Breastfeeding
Because the Misoprostol component can cause miscarriage, this combination must not be used by women who are pregnant. Diclofenac Sodium does pass into breast milk, so Diclofenac Sodium plus Misoprostol is not advised for mothers who are breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.