Bricoma OSD Brimonidine Tartrate Clonidine Hydrochloride
ModerateTricyclic antidepressants have been reported to blunt the hypotensive effect of systemic clonidine. It is not known whether the concurrent use of these agents with Brimodin ophthalmic solution in humans can lead to resulting interference with the IOP lowering effect.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.