Sumatriptan

Adults: Sumatriptan nasal spray: A single dose is 10 mg. The maximum dose in any 24-hour period is 30 mg. Doses should be separated by at least one hour, or as directed by the physician. Sumatriptan tablets: In controlled clinical trials, single doses of 25 mg, 50 mg or 100 mg were effective for the acute treatment of migraine in adults. Evidence suggests that 50 mg and 100 mg doses may work better than 25 mg, but that 100 mg does not work better than 50 mg. Because people respond differently to Sumatriptan tablets, the dose should be chosen for each patient individually, weighing the possible benefit of a higher dose against the greater risk of side effects. If the headache returns, or if the patient has only a partial response to the first dose, the dose may be repeated after 2 hours. The total daily dose should not exceed 200 mg. If a headache returns after initial treatment with Sumatriptan injection, additional single Sumatriptan tablets (up to 100 mg per day) may be given, with at least 2 hours between tablet doses. The safety of treating more than an average of 4 headaches in a 30-day period has not been established. Use in children and adolescents: Sumatriptan is not recommended for patients under 18 years of age.