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Other brands with the same active ingredient
These brands contain the same active ingredient (Sumatriptan). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Sumatriptan nasal spray: A single dose is 10 mg. The maximum dose in any 24-hour period is 30 mg. Doses should be separated by at least one hour, or as directed by the physician. Sumatriptan tablets: In controlled clinical trials, single doses of 25 mg, 50 mg or 100 mg were effective for the acute treatment of migraine in adults. Evidence suggests that 50 mg and 100 mg doses may work better than 25 mg, but that 100 mg does not work better than 50 mg. Because people respond differently to Sumatriptan tablets, the dose should be chosen for each patient individually, weighing the possible benefit of a higher dose against the greater risk of side effects. If the headache returns, or if the patient has only a partial response to the first dose, the dose may be repeated after 2 hours. The total daily dose should not exceed 200 mg. If a headache returns after initial treatment with Sumatriptan injection, additional single Sumatriptan tablets (up to 100 mg per day) may be given, with at least 2 hours between tablet doses. The safety of treating more than an average of 4 headaches in a 30-day period has not been established. Use in children and adolescents: Sumatriptan is not recommended for patients under 18 years of age.
Side Effects
Common side effects of the nasal spray include an unusual or unpleasant taste in the mouth; pain, burning, numbness or tingling in the nose or throat; and a runny or blocked nose after use. Less commonly, people may experience anxiety, a burning sensation, discomfort in the nose and throat, a general feeling of being unwell or tired, and changes in vision.
Cautions & Contraindications
Warnings & Precautions
Myocardial ischemia, infarction and Prinzmetal's angina: patients with several cardiovascular risk factors should have a cardiac evaluation before use. Arrhythmias: stop Sumatrex if an arrhythmia develops. Chest, throat, neck or jaw pain, tightness, pressure or heaviness: these are generally not associated with myocardial ischemia, but patients at high risk should be evaluated for coronary artery disease. Cerebral hemorrhage, subarachnoid hemorrhage and stroke: stop Sumatrex if any of these occurs. Gastrointestinal ischemia and reactions, and peripheral vasospastic reactions: stop Sumatrex if these occur. Medication overuse headache: detoxification may be necessary. Serotonin syndrome: stop Sumatrex if it occurs. Increase in blood pressure: a hypertensive crisis can occur. Hypersensitivity reactions: angioedema and anaphylaxis can occur. Seizures: use with caution in patients with epilepsy or a lowered seizure threshold. Local irritation: burning and an abnormal taste can occur.
Contraindications
History of coronary artery disease or coronary vasospasm Wolff-Parkinson-White syndrome or other cardiac accessory conduction pathway disorders History of stroke, transient ischemic attack, or hemiplegic or basilar migraine Peripheral vascular disease Ischemic bowel disease Uncontrolled hypertension Recent (within 24 hours) use of another 5 HT1 agonist (e.g., another triptan) or of an ergotamine containing medication Concurrent or recent (past 2 weeks) use of monoamine oxidase A inhibitor Hypersensitivity to sumatriptan (angioedema and anaphylaxis seen) Severe hepatic impairment