Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Treats life-threatening arrhythmias, including ventricular tachyarrhythmias and symptomatic non-sustained ventricular tachyarrhythmia. Also used to prevent paroxysmal atrial tachycardia or fibrillation, and paroxysmal AV re-entrant tachycardias (both nodal and those involving accessory pathways). Given for paroxysmal supraventricular tachycardia following cardiac surgery, and to help maintain normal heart rhythm after cardioversion of atrial fibrillation or flutter.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Sotalol is a non-cardioselective beta-blocker that lengthens the sinus cycle and slows the heart rate. It also decreases AV nodal conduction while increasing AV nodal refractoriness, and it prolongs AV monophasic action potentials. However, it lacks intrinsic sympathomimetic and membrane-stabilising properties.

Pregnancy & Breastfeeding

Its use during pregnancy should be avoided unless clearly necessary, since it crosses the placenta and may slow the baby's heart rate (foetal bradycardia). Mothers being treated with Sotalol should not breastfeed.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Initially 80 mg daily in 1 to 2 divided doses. After ECG monitoring and measurement of corrected QT interval and arrhythmias, the dose is increased gradually at intervals of 2 to 3 days to a usual dose of 160 to 320 mg daily in 2 divided doses; higher doses of 480 to 640 mg daily may be used for life-threatening ventricular arrhythmias under specialist supervision. The dosage should be reduced in renal impairment. If creatinine clearance is greater than 60 ml/min, the recommended dose is 160 mg twice daily, while in those with creatinine clearance between 40 and 60 ml/min, the dose is given once daily. In patients with creatinine clearance less than 40 ml/min, Sotalol is contraindicated.

Side Effects & Interactions