Indications
Vasculex injection is used to treat significant low blood pressure that occurs mainly due to blood vessel widening during anesthesia.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Phenylephrine is an alpha-1 adrenergic receptor agonist. Following intravenous administration of phenylephrine, increases in systolic and diastolic blood pressures and arterial blood pressure are observed. The onset of blood pressure increase is rapid, typically within minutes. Following intravenous administration of phenylephrine hydrochloride, increases in systolic and diastolic blood pressures, mean arterial blood pressure, and total peripheral vascular resistance are observed. The onset of blood pressure increase following an intravenous bolus dose of phenylephrine hydrochloride is rapid, typically within minutes. As blood pressure increases following intravenous administration, vagal activity also increases, resulting in reflex bradycardia. Phenylephrine acts on most vascular beds, including the renal, pulmonary, and splanchnic arteries.
Pregnancy & Breastfeeding
Data from randomized controlled trials and meta-analyses of Phenylephrine injection used during caesarean section have not shown a drug-related risk of major birth defects or miscarriage. No data are available on its use during the first or second trimester. It is also not known whether Phenylephrine injection or its metabolite passes into human or animal breast milk, nor whether it affects the breastfed infant or milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.