Indications
Diaset, used alone, is meant to be taken alongside diet and exercise to help control blood sugar in people with Type II diabetes whose high blood sugar isn't adequately managed by diet alone. It can also be combined with a sulfonylurea if diet plus Diaset alone, or diet plus a sulfonylurea alone, isn't giving enough blood sugar control.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Miglitol is derived from desoxynojirimycin. It does not increase insulin secretion. Its blood-sugar-lowering effect comes from reversibly blocking the membrane-bound alpha-glucoside hydrolase enzymes found in the intestine. These enzymes normally break down oligosaccharides and disaccharides into glucose and other simple sugars at the brush border of the small intestine. By inhibiting them, Miglitol delays glucose absorption in diabetic patients and reduces the rise in blood sugar that occurs after meals. Because it lowers plasma glucose in this way, Miglitol also reduces levels of glycosylated hemoglobin.
Pregnancy & Breastfeeding
Miglitol falls under pregnancy category B. Its safety in pregnant women has not been firmly established, and because there are no adequate, well-controlled studies to confirm this, it should only be used during pregnancy if clearly necessary. Miglitol does pass into human breast milk, though only in very small amounts. Even at these low levels, nursing mothers are advised not to take Miglitol.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.