Indications
Fluvate helps relieve the itching and inflammation caused by eczema and dermatitis that respond to corticosteroid treatment.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Fluticasone propionate is a glucocorticoid with strong topical anti-inflammatory potency but low HPA-axis suppressive activity after dermal administration. As a result, its therapeutic index is greater than that of most commonly available steroids. Fluticasone propionate shows a high degree of selectivity for the glucocorticoid receptor. In vitro studies show that it has strong affinity for, and agonist activity at, human glucocorticoid receptors, the receptor believed to be responsible for the anti-inflammatory properties of glucocorticoids. Fluticasone propionate has weak affinity for the progesterone receptor and virtually no affinity for the mineralocorticoid, estrogen, or androgen receptors. The therapeutic potency of glucocorticoids is related to the half-life of the glucocorticoid receptor complex, and for fluticasone propionate this half-life is approximately 10 hours.
Pregnancy & Breastfeeding
Administration of fluticasone propionate during pregnancy should only be considered if the expected benefit to the mother outweighs any possible risk to the unborn baby. Whether fluticasone propionate passes into human breast milk has not been studied. However, when applied to the skin at the recommended doses, only small amounts are likely to reach the bloodstream. If use during breastfeeding is being considered, the therapeutic benefits should be weighed against the potential risks to both mother and baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.