Fluair 500 Unicap
Rx500 mcg • Inhalation Capsule
Indications & Uses
Fluair 500 Unicap is indicated for:
Pharmacology
Fluticasone propionate is a glucocorticoid with strong topical anti-inflammatory potency but low HPA-axis suppressive activity after dermal administration. As a result, its therapeutic index is greater than that of most commonly available steroids. Fluticasone propionate shows a high degree of selectivity for the glucocorticoid receptor. In vitro studies show that it has strong affinity for, and agonist activity at, human glucocorticoid receptors, the receptor believed to be responsible for the anti-inflammatory properties of glucocorticoids. Fluticasone propionate has weak affinity for the progesterone receptor and virtually no affinity for the mineralocorticoid, estrogen, or androgen receptors. The therapeutic potency of glucocorticoids is related to the half-life of the glucocorticoid receptor complex, and for fluticasone propionate this half-life is approximately 10 hours.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Apply a thin layer of Fluticasone Propionate cream to the affected area of skin once a day.
Apply a thin layer of Fluticasone Propionate ointment to the affected area of skin twice a day.
Side Effects
The Fluvate preparations are generally well tolerated, though local burning and itching have been reported. If any sign of hypersensitivity appears, treatment should be stopped straight away. With prolonged, intensive use of potent corticosteroid preparations, local atrophic changes in the skin can develop, such as thinning, stretch marks, widening of the small surface blood vessels, excess hair growth and loss of skin pigment. Secondary infection has also been reported with corticosteroid use, particularly where occlusive dressings are used or skin folds are involved, along with allergic contact dermatitis. Corticosteroid use has likewise been linked to worsening of the underlying skin condition being treated. Prolonged use of large amounts of corticosteroid, or treatment over extensive areas, can lead to enough absorption into the body to produce features of hypercorticism. This is more likely in infants and children, and where occlusive dressings are used; in infants, a napkin (nappy) can itself act as an occlusive dressing.
Cautions & Contraindications
Warnings & Precautions
Fluvate is absorbed into the bloodstream only to a very limited extent. Even so, using high doses over large areas of skin for a long time can suppress adrenal gland function, particularly in infants and young children. Because children may absorb proportionally more of a topical corticosteroid than adults, they can be more prone to these body-wide effects. The face tends to be more susceptible than other areas to thinning of the skin after prolonged use of potent topical corticosteroids, which is worth keeping in mind when treating severe eczema. If the skin lesions being treated become infected, a suitable antimicrobial medicine should be added to the treatment. If the infection spreads, the corticosteroid should be stopped and an antimicrobial given by mouth or injection. Occlusive dressings create warm, moist conditions that can encourage bacterial growth, so the skin should be cleaned each time before a fresh dressing is applied.
Contraindications
Fluticasone propionate should not be used by anyone with rosacea, acne vulgaris, perioral dermatitis, or a known hypersensitivity to any of its ingredients. It is also unsuitable for primary viral skin infections such as herpes simplex or chickenpox, and it should be avoided for pruritus affecting the perianal or genital area, among other conditions. More broadly, this medicine is not meant for treating skin lesions that are primarily infected with fungi or bacteria. It should likewise not be given to children under one year of age for skin conditions, including dermatitis and napkin (diaper) rash.
Pregnancy & Breastfeeding
Administration of fluticasone propionate during pregnancy should only be considered if the expected benefit to the mother outweighs any possible risk to the unborn baby. Whether fluticasone propionate passes into human breast milk has not been studied. However, when applied to the skin at the recommended doses, only small amounts are likely to reach the bloodstream. If use during breastfeeding is being considered, the therapeutic benefits should be weighed against the potential risks to both mother and baby.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Acute overdosage is very unlikely to occur, however, in case of chronic overdosage or misuse the features of hypercorticism may appear, and in this situation, as with any corticosteroid, the application should be discontinued. Overdosage by ingestion of Fluticasone Propionate cream or ointment is extremely unlikely to occur due to the very low oral bioavailability of Fluticasone Propionate.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store below 30°C.Do not freeze.
Drug Interactions
Common questions about Fluair 500 Unicap 500 mcg
What is Fluair 500 Unicap 500 mcg Inhalation Capsule?
Fluair 500 Unicap 500 mcg Inhalation Capsule is a medicine that contains Fluticasone Propionate. It is made by Unimed Unihealth Pharmaceuticals Ltd. It belongs to the Fluocinolone & Combined Preparations group of medicines.
What is Fluair 500 Unicap used for?
Fluair 500 Unicap is used for: Eczema.
What are the side effects of Fluair 500 Unicap?
The Fluvate preparations are generally well tolerated, though local burning and itching have been reported. If any sign of hypersensitivity appears, treatment should be stopped straight away.
Can I take Fluair 500 Unicap during pregnancy or while breastfeeding?
Administration of fluticasone propionate during pregnancy should only be considered if the expected benefit to the mother outweighs any possible risk to the unborn baby. Whether fluticasone propionate passes into human breast milk has not been studied. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Fluair 500 Unicap?
Acute overdosage is very unlikely to occur, however, in case of chronic overdosage or misuse the features of hypercorticism may appear, and in this situation, as with any corticosteroid, the application should be discontinued. Overdosage by ingestion of Fluticasone Propionate cream or ointment is extremely unlikely to occur due to the very low oral bioavailability of Fluticasone Propionate. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Fluair 500 Unicap?
Store below 30°C.Do not freeze.
Can I take other medicines with Fluair 500 Unicap?
Some medicines can interact with Fluticasone Propionate, for example: Salmeterol + Fluticasone Propionate. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Fluair 500 Unicap?
Fluair 500 Unicap is a prescription (Rx) medicine. Take it as your doctor advises.