Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Fenazine is prescribed for the long-term management of psychotic disorders, including schizophrenia, mania, and organic brain syndrome.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Fluphenazine decanoate works by blocking dopamine D1 and D2 receptors after the synapse in the brain's mesolimbic pathway, and it also cuts down the release of hypothalamic and pituitary hormones. This action brings on a sense of calm, eases aggressive behaviour, and clears away hallucinations and delusions. As a derivative of the phenothiazine group, fluphenazine decanoate is a highly potent antipsychotic given by intramuscular injection, valued for how long its effects last. Attaching decanoic acid to the fluphenazine molecule through esterification is what stretches out this duration of action, and it does so without making the drug any less effective.

Pregnancy & Breastfeeding

Safety during pregnancy has not been established for Fluphenazine decanoate, so it should only be given to pregnant patients after weighing the potential benefits against the possible risks.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Fluphenazine Decanoate is given by deep intramuscular injection into the gluteal muscle. A test dose of 12.5 mg is given first (6.25 mg in the elderly), then, after 4 to 7 days, 12.5 to 100 mg is given at intervals of 14 to 35 days, adjusted according to response. It is not recommended for children.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.