Indications & Uses
Fenazine is prescribed for the long-term management of psychotic disorders, including schizophrenia, mania, and organic brain syndrome.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Fluphenazine Decanoate is given by deep intramuscular injection into the gluteal muscle. A test dose of 12.5 mg is given first (6.25 mg in the elderly), then, after 4 to 7 days, 12.5 to 100 mg is given at intervals of 14 to 35 days, adjusted according to response. It is not recommended for children.
Side Effects
Tardive dyskinesia, sedation, and mental confusion can occur, along with a drop in blood pressure. By raising prolactin levels, the medicine may cause galactorrhoea and amenorrhoea in women, and reduced libido, impotence, or sterility in men. Allergic reactions, cholestatic jaundice, deposits in the cornea and lens, and skin pigmentation are also seen. Less commonly, it may lead to agranulocytosis or neuroleptic malignant syndrome.
Cautions & Contraindications
Warnings & Precautions
Special caution is needed for patients with convulsive disorders or hepatic, renal, cerebrovascular, respiratory, or cardiovascular disease. Caution should also be used in pheochromocytoma, bone marrow suppression, and in elderly or debilitated patients.
Contraindications
Fluphenazine Decanoate oily injection should not be used in patients known to be hypersensitive to it. It should also be avoided in those who are comatose or in a state of severe depression, as well as in patients with blood disorders (blood dyscrasias) or liver disease. It should not be used during the 3rd trimester of pregnancy or while breastfeeding.