Flunarizine

Adults: Migraine Prophylaxis: The starting dose is 10 mg at night for patients under 65 years of age, and 5 mg daily for patients over 65 years. If depressive, extrapyramidal or other unacceptable symptoms occur during this treatment, it should be stopped. If no significant improvement is seen after 2 months of this initial treatment, the patient should be considered a non-responder and the medicine should be discontinued. Maintenance Treatment: If a patient is responding well and maintenance treatment is needed, the dose should be reduced to 5 days of treatment at the same daily dose, with two consecutive medicine free days each week. Even when prophylactic maintenance treatment is successful and well tolerated, it should be stopped after 6 months and restarted only if the patient relapses. Peripheral Vascular Disease: 10 mg twice daily, up to 30 mg per day if required. Vertigo and Motion Sickness: 10 to 20 mg daily for adults and 5 mg daily for children over 40 kg. Epileptic Seizure: 15 to 20 mg daily for adults and 5 to 10 mg daily for children, as an add on therapy.