Informational only — Not medical advice. Always consult a licensed healthcare provider.

MedBD
বাং
Community data Updated 2 months ago
🌐 বাংলায় দেখুন

Indications

Adiva in combination with other antiretroviral agents is indicated for the treatment of HIV-1 infection. This indication is based on analyses of plasma HIV- RNA levels and CD4 cell counts in controlled studies of up to 24 weeks in duration. At present, there are no results from controlled trials evaluating long term suppression of HIVRNA with Adiva.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) active against HIV-1. It blocks RNA and DNA dependent polymerase activities, including HIV-1 replication.

Pregnancy & Breastfeeding

Category D: There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).Lactation: Efavirenz may pass through breast milk and cause serious harm to the baby. It should not be used during lactation.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dosage in Adults: The recommended dose of Efavirenz is 600 mg taken by mouth once daily, combined with a protease inhibitor and/or nucleoside analogue reverse transcriptase inhibitors (NRTIs). Dosage in Pediatric Patients: For children 3 years of age or older weighing between 10 and 40 kg, the recommended dose of Efavirenz depends on body weight. Children weighing 10 to less than 15 kg should receive 200 mg once daily. Those weighing 15 to less than 20 kg should receive 250 mg once daily. Those weighing 20 to less than 25 kg should receive 300 mg once daily. Those weighing 25 to less than 32.5 kg should receive 350 mg once daily. Those weighing 32.5 to less than 40 kg should receive 400 mg once daily. Children weighing 40 kg or more, as well as those weighing more than 40 kg, should receive the same dose used in adults, which is 600 mg once daily.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.