Diclofenac Sodium + Lidocaine Hydrochloride
Indications
This injection combines Diclofenac Sodium with Lidocaine Hydrochloride. Diclofenac Sodium relieves pain and inflammation of all grades across a wide range of conditions, including arthritic conditions such as rheumatoid arthritis, osteoarthritis, juvenile chronic arthritis, ankylosing spondylitis, and acute gout; acute musculoskeletal disorders such as periarthritis (for example, frozen shoulder), tendinitis, tenosynovitis, and bursitis; and other painful conditions arising from trauma, including fractures, low back pain, sprains, strains, and dislocations. It is also used to control pain and inflammation following orthopaedic, dental, and other minor surgeries, for postoperative pain, and for the pain of renal colic, among other conditions. The Lidocaine in this injection acts as a local anaesthetic, so when this combination is used for the indications above, it minimizes the pain at the injection site that most often occurs with intramuscular injection.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Diclofenac Sodium is a potent nonsteroidal anti-inflammatory drug (NSAID) with marked pain-relieving and fever-reducing properties, along with some uricosuric effect. Its action appears to be linked to the inhibition of prostaglandin synthesis: Diclofenac blocks cyclooxygenase, the enzyme responsible for converting arachidonic acid into prostaglandin precursors. After injection, peak plasma concentration is reached within half an hour.
Lidocaine Hydrochloride is the most widely used local anaesthetic. It works faster and is more stable than most other local anaesthetics, making it a very useful surface anaesthetic. Like other local anaesthetics, it impairs the generation and conduction of nerve impulses by slowing depolarization. Its onset of anaesthesia is rapid, with effects lasting 1 to 2 hours.
Pregnancy & Breastfeeding
Pregnancy: This medicine should not be used during pregnancy unless the potential benefit clearly justifies the risk, and if it must be used, the lowest effective dose is advised. It is not recommended in the final trimester of pregnancy.
Breastfeeding: Only trace amounts of Diclofenac pass into breast milk, and at these levels the infant is not expected to experience any harmful effects.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.