Edifenac Plus
Rx75 mg+20 mg • IM Injection
Indications & Uses
Edifenac Plus is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults: One ampoule given once daily by intramuscular injection; in severe cases, this may be increased to twice daily. For renal colic, one ampoule is given once daily by intramuscular injection, with a second dose after 30 minutes if needed. Children: For juvenile chronic arthritis, 1 to 3 mg of Diclofenac Sodium per kg of body weight daily, given in divided doses. Elderly patients: Elderly or debilitated patients should generally be given the lowest effective dose, based on their age and physical condition, or as advised by the physician.
Side Effects
Side effects with Diclofenac Sodium and Lidocaine injection are usually mild and transient, but the injection should be stopped if a serious reaction develops. Patients may notice gastrointestinal discomfort, nausea, diarrhea and, occasionally, bleeding. Very rarely, disorders at the injection site can occur, and isolated cases of abscess and local tissue necrosis have been reported. Effects attributable to the Lidocaine component mainly involve the CNS; these are usually brief and dose related, and may show up as drowsiness, dizziness, disorientation, confusion, lightheadedness and similar CNS symptoms.
Cautions & Contraindications
Warnings & Precautions
Renal: Patients with severe liver, heart, or kidney impairment, as well as elderly patients, should be closely monitored, since NSAIDs like this one can worsen kidney function. The lowest effective dose should be used, and kidney function should be checked periodically. Hepatic: If liver function tests remain abnormal or worsen, if signs or symptoms of liver disease appear, or if other reactions such as eosinophilia or rash occur, Diclofenac should be stopped. All patients on long-term NSAID therapy should be monitored regularly as a precaution, including checks of kidney function, liver function, and blood counts.
Contraindications
Contraindicated in patients hypersensitive to Diclofenac. It should also not be used in those with active or suspected peptic ulcer, gastrointestinal bleeding, or a history of asthma attacks, urticaria, or acute rhinitis triggered by Aspirin or other NSAIDs with prostaglandin synthetase-inhibiting activity. Because it contains Lidocaine, this injection is likewise contraindicated in patients hypersensitive to amide-type local anaesthetics, though such reactions are very rare. It should not be given to patients with Adams-Stokes syndrome or severe SA, AV, or intraventricular heart block who do not have an artificial pacemaker in place, or to those hypersensitive to any excipient in the formulation (Sodium Metabisulphite, Disodium Edetate, Benzyl Alcohol, Sodium Hydroxide, Propylene Glycol).