Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Cabolin is used to stop breast milk production (lactation) soon after childbirth, stillbirth, abortion or miscarriage. It can also be used by mothers who choose not to continue breastfeeding. Beyond this, Cabolin is used to treat other conditions caused by hormonal disturbances that lead to abnormally high levels of prolactin.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Cabergoline is a dopamine receptor agonist. The anterior pituitary's secretion of prolactin is mainly under hypothalamic inhibitory control, likely exerted through dopamine release from tuberoinfundibular neurons. Cabergoline is a long acting dopamine receptor agonist with a high affinity for D2 receptors. In vitro studies show that Cabergoline directly inhibits prolactin secretion by rat pituitary lactotrophs. Cabergoline also decreased serum prolactin levels in reserpinized rats. Receptor binding studies indicate that Cabergoline has low affinity for dopamine D1, α1 and α2 adrenergic, and 5HT1, 5HT2 serotonin receptors.

Pregnancy & Breastfeeding

Pregnant or planning to get pregnant, discuss this with doctor before treatment though the pregnancy category B. Before start using Cabergoline check that patient not pregnant. Pregnant for at least one month once havestopped taking Cabergoline, As Ferticab will stop producing milk.If someone plan to breastfeed should not take Cabergoline.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: The recommended starting dose of Cabergoline is 0.25 mg twice a week. Depending on the patient's serum prolactin level, the dose may be raised by 0.25 mg twice weekly, up to a maximum of 1 mg twice a week. Increases should be spaced at least 4 weeks apart so the physician can properly judge the response at each level. If higher doses bring no extra benefit, the lowest dose that gave the best response should be continued, and other treatment options considered. Once a normal serum prolactin level has been maintained for 6 months, Cabergoline can be stopped, with periodic prolactin checks afterward to see whether treatment needs to start again. To prevent milk production after delivery: a single 1 mg dose of Cabergoline, taken on the first day after delivery. To stop lactation after breastfeeding has already begun: 0.25 mg every 12 hours for two days. To lower prolactin levels in other conditions: treatment usually starts with one 0.5 mg tablet, split into two doses taken a few days apart over the week (for example, half a tablet on Monday and the other half on Thursday). The dose can then be raised gradually, up to a maximum of 4.5 mg, until a full response to treatment is achieved.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.