Indications
Baclax is used to treat spasticity caused by multiple sclerosis, including flexor spasms with associated pain, clonus, and muscle rigidity. It also relieves skeletal muscle spasm arising from rheumatic disorders, spinal cord injuries and other spinal cord diseases, stroke, and brain disease caused by tumors or degeneration.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Baclofen blocks monosynaptic and polysynaptic reflexes at the spinal level by stimulating GABAB receptors, which suppresses release of glutamate and aspartate. It may also act at intraspinal sites to produce CNS depression, and it has an antinociceptive effect as well.
Pregnancy & Breastfeeding
Pregnancy category B3. The safety of Baclofen in pregnancy has not been firmly established, and it is known to cross the placental barrier. For this reason, it should only be given to a pregnant woman if her physician judges that the likely benefits outweigh the possible risks. Baclofen does pass into breast milk, but the amounts involved appear to be small enough that no harmful effects on the breastfed infant would be expected.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.