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Other brands with the same active ingredient
These brands contain the same active ingredient (Baclofen). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Laxifen 5 is indicated for:
Pharmacology
Baclofen blocks monosynaptic and polysynaptic reflexes at the spinal level by stimulating GABAB receptors, which suppresses release of glutamate and aspartate. It may also act at intraspinal sites to produce CNS depression, and it has an antinociceptive effect as well.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults and children over 10 years: 5 mg 3 times daily, preferably with or after food, gradually increased as needed; maximum 100 mg daily. Children under 10 years: treatment is usually started with 2.5 mg (2.5 ml) given 4 times daily, then raised according to requirement. Daily maintenance dose: 12 months to 2 years, 10 to 20 mg (10 to 20 ml); 2 years to 6 years, 20 to 30 mg (20 to 30 ml); 6 years to 10 years, 30 to 60 mg (30 to 60 ml).
Side Effects
Baclax most commonly causes transient drowsiness, daytime sedation, dizziness, weakness and fatigue. Central nervous system: headache (under 10%); insomnia (under 10%); and rarely, euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, coordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizures and respiratory depression. Cardiovascular: hypotension (under 10%); and rarely, breathlessness, palpitation, chest pain and fainting. Gastrointestinal: nausea (about 10%); constipation (under 10%); and rarely, dry mouth, loss of appetite, taste disturbance, abdominal pain, vomiting, diarrhoea and a positive test for occult blood in the stool. Genitourinary: frequent urination (under 10%); and rarely, bedwetting, urinary retention, painful urination, impotence, inability to ejaculate, nighttime urination and blood in the urine. Other effects that have been reported include rash, itching, ankle swelling, excessive sweating, weight gain, nasal congestion, visual disturbances, disorders of liver function and a paradoxical increase in muscle spasticity. Muscle weakness severe enough to make walking or movement difficult can occur, but this usually improves once the dose is adjusted. In such cases, the daytime dose may be lowered and the evening dose increased.
Cautions & Contraindications
Warnings & Precautions
Lower doses (approximately 5 mg per day) should be used for patients with impaired kidney function or those undergoing long-term haemodialysis. Patients who have spasticity along with psychotic disorders, schizophrenia, depressive or manic disorders, or confusional states should be treated cautiously and monitored closely, since these conditions may worsen. In patients with epilepsy and muscle spasticity, Baclax may be used under appropriate supervision, provided that adequate anticonvulsive therapy is continued. The seizure threshold may be lowered, and seizures have been reported both after stopping Baclax therapy and with overdose. Baclax should be used with caution in patients who have, or have a history of, peptic ulcers, cerebrovascular disease, or hepatic, renal, or respiratory failure. Careful monitoring of respiratory and cardiovascular function is essential, particularly in patients with cardiopulmonary disease and respiratory muscle weakness. During treatment with Baclax, nerve related problems affecting bladder emptying may improve. However, in patients with pre-existing sphincter hypertonia, acute urinary retention may occur, so Baclax should be used with caution in these cases. Baclax has not provided significant benefit to patients who have had a stroke, and such patients have also shown poor tolerance to the medicine. Appropriate laboratory tests should be carried out periodically in patients with liver disease or diabetes mellitus, to check that the medicine has not caused any change in these underlying conditions.
Contraindications
Baclofen should not be used by anyone who is hypersensitive to it or to any other ingredient in this product.
Pregnancy & Breastfeeding
Pregnancy category B3. The safety of Baclofen in pregnancy has not been firmly established, and it is known to cross the placental barrier. For this reason, it should only be given to a pregnant woman if her physician judges that the likely benefits outweigh the possible risks. Baclofen does pass into breast milk, but the amounts involved appear to be small enough that no harmful effects on the breastfed infant would be expected.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In a severe overdose of Baclofen, gastric lavage is important.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Baclofen below 30°C, away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Laxifen 5 5 mg
What is Laxifen 5 5 mg Tablet?
Laxifen 5 5 mg Tablet is a medicine that contains Baclofen. It is made by National Drug Company Ltd. It belongs to the Centrally acting Skeletal Muscle Relaxants group of medicines.
What is Laxifen 5 used for?
Laxifen 5 is used for: Pain, Muscle Spasm.
What are the side effects of Laxifen 5?
Baclax most commonly causes transient drowsiness, daytime sedation, dizziness, weakness and fatigue. Central nervous system: headache (under 10%); insomnia (under 10%); and rarely, euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, coordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizures and respiratory depression.
Can I take Laxifen 5 during pregnancy or while breastfeeding?
Pregnancy category B3. The safety of Baclofen in pregnancy has not been firmly established, and it is known to cross the placental barrier. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Laxifen 5?
In a severe overdose of Baclofen, gastric lavage is important. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Laxifen 5?
Store Baclofen below 30°C, away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Laxifen 5?
Some medicines can interact with Baclofen, for example: Memantine Hydrochloride, Magnesium Sulphate, Levodopa, Magnesium, Eplerenone, Triamterene + Hydrochlorothiazide. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Laxifen 5?
Laxifen 5 is a prescription (Rx) medicine. Take it as your doctor advises.