Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago
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Indications

Hypertension Angina Pectoris Myocardial Infarction

Tensin is used to treat high blood pressure, either alone or together with other antihypertensive medicines, particularly a thiazide-type diuretic. It is also used for the long-term management of angina pectoris, and in hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce the risk of cardiovascular death.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Atenolol was developed in the search for a β-adrenoceptor antagonist that would block β1 (cardiac) receptors selectively, without affecting β2-receptors. It is classified as a β1-selective (cardioselective) β-adrenergic receptor antagonist, with no membrane-stabilising activity and no partial agonist activity. Among the β-blockers currently available, it is the most hydrophilic, and for this reason it penetrates the lipid layer of cell membranes poorly.

Pregnancy & Breastfeeding

Pregnancy Category D. Atenolol should be used cautiously in breastfeeding mothers, as clinically significant bradycardia has been reported in infants who were breastfed while their mothers took this medicine. Premature babies and those with reduced kidney function may be more prone to such effects.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Hypertension: The initial dose of Atenolol is 50 mg, taken as one tablet daily, either alone or added to diuretic therapy. The full effect of this dose is usually seen within one to two weeks. If the response is not optimal, the dose should be increased to 100 mg of Atenolol as one tablet daily. Increasing the dose beyond 100 mg a day is unlikely to give any further benefit. Angina Pectoris: The initial dose of Atenolol is 50 mg given as one tablet daily. If the response is not optimal within one week, the dose should be increased to 100 mg of Atenolol as one tablet daily. Some patients may need a dose of 200 mg once daily for the best effect. Full, twenty four hour control with once daily dosing is achieved by giving doses larger than what is needed for an immediate maximum effect. The greatest early effect on exercise tolerance occurs with doses of 50 to 100 mg, but at these doses the effect at 24 hours is reduced, averaging about 50% to 75% of that seen with a once daily oral dose of 200 mg. Acute Myocardial Infarction: In patients with definite or suspected acute myocardial infarction, treatment with Atenolol I.V. Injection should begin as soon as possible after the patient arrives at the hospital and eligibility is confirmed. Treatment should start with an intravenous dose of 5 mg Atenolol given over 5 minutes, followed by another 5 mg intravenous injection 10 minutes later. In patients who tolerate the full intravenous dose (10 mg), Atenolol Tablets 50 mg should be started 10 minutes after the last intravenous dose, followed by another 50 mg oral dose 12 hours later. After this, Atenolol can be given orally, either 100 mg once daily or 50 mg twice daily, for a further 6 to 9 days or until discharge from the hospital. If bradycardia or hypotension needing treatment, or any other unwanted effects occur, Atenolol should be stopped.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.