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These brands contain the same active ingredient (Atenolol). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Cardisef is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Hypertension: The initial dose of Atenolol is 50 mg, taken as one tablet daily, either alone or added to diuretic therapy. The full effect of this dose is usually seen within one to two weeks. If the response is not optimal, the dose should be increased to 100 mg of Atenolol as one tablet daily. Increasing the dose beyond 100 mg a day is unlikely to give any further benefit. Angina Pectoris: The initial dose of Atenolol is 50 mg given as one tablet daily. If the response is not optimal within one week, the dose should be increased to 100 mg of Atenolol as one tablet daily. Some patients may need a dose of 200 mg once daily for the best effect. Full, twenty four hour control with once daily dosing is achieved by giving doses larger than what is needed for an immediate maximum effect. The greatest early effect on exercise tolerance occurs with doses of 50 to 100 mg, but at these doses the effect at 24 hours is reduced, averaging about 50% to 75% of that seen with a once daily oral dose of 200 mg. Acute Myocardial Infarction: In patients with definite or suspected acute myocardial infarction, treatment with Atenolol I.V. Injection should begin as soon as possible after the patient arrives at the hospital and eligibility is confirmed. Treatment should start with an intravenous dose of 5 mg Atenolol given over 5 minutes, followed by another 5 mg intravenous injection 10 minutes later. In patients who tolerate the full intravenous dose (10 mg), Atenolol Tablets 50 mg should be started 10 minutes after the last intravenous dose, followed by another 50 mg oral dose 12 hours later. After this, Atenolol can be given orally, either 100 mg once daily or 50 mg twice daily, for a further 6 to 9 days or until discharge from the hospital. If bradycardia or hypotension needing treatment, or any other unwanted effects occur, Atenolol should be stopped.
Side Effects
In studies looking at atenolol's use after a heart attack, slow heart rate and low blood pressure occurred more often, which is expected for any beta blocker. Beyond this, a range of other side effects has been reported with beta-adrenergic blocking drugs generally, and these should be considered possible side effects of Tensin as well. Blood disorders: a severe drop in a type of white blood cell (agranulocytosis). Allergic reactions: fever along with body aches and sore throat, spasm of the voice box, and difficulty breathing. Nervous system: mental depression that can progress to a state of unresponsiveness (catatonia) if not reversed; a temporary episode of confusion about time and place; short-term memory loss; emotional instability with mild clouding of alertness; and reduced performance on tests of mental function. Digestive system: blood clots in the arteries supplying the intestines, and reduced blood flow to the colon (ischemic colitis). Other reported effects: skin rashes and/or dry eyes have been associated with beta-adrenergic blocking drugs in general, as has a reddish skin rash. If any of these reactions occurs without another clear explanation, stopping the medicine should be considered, and patients should be watched closely after treatment ends.
Cautions & Contraindications
Warnings & Precautions
General: Patients already taking a beta blocker should be carefully evaluated before starting Tensin. The initial and follow-up doses of Tensin may need to be adjusted downward based on clinical findings, including pulse rate and blood pressure. Tensin may worsen peripheral arterial circulatory disorders. Impaired Renal Function: This medicine should be used with caution in patients who have impaired kidney function. Geriatric Use: For hypertension and angina pectoris due to coronary atherosclerosis, dose selection in elderly patients should be cautious, usually starting at the lower end of the dosing range, since these patients more often have reduced hepatic, renal, or cardiac function, as well as concurrent illness or other drug therapy. The same caution applies to dosing after acute myocardial infarction, again starting at the lower end of the range for the same reasons. Evaluation of elderly patients with hypertension or myocardial infarction should always include an assessment of kidney function.
Contraindications
Atenolol should not be used in patients with sinus bradycardia, heart block more severe than first degree, cardiogenic shock, or overt heart failure. It is also not suitable for anyone with a known hypersensitivity to atenolol or to any other ingredient in the product.