Indications
Simox DS is used to treat infections caused by susceptible ß-lactamase negative organisms. These include ear, nose and throat infections such as otitis media, sinusitis, tonsillitis, pharyngitis and laryngitis, and lower respiratory tract infections such as pneumonia, acute and chronic bronchitis, lung abscess, empyema and bronchiectasis. It also treats skin and soft tissue infections such as cellulitis, carbuncles, furunculosis, infected wounds and abscess, genito-urinary tract infections such as pyelonephritis, cystitis and urethritis, and venereal disease such as acute uncomplicated gonorrhoea. For dental abscess, it is used as short-term therapy. It is also given together with clarithromycin and lansoprazole as triple therapy to treat patients with H. pylori infection and duodenal ulcer disease, and to reduce the risk of duodenal ulcer recurrence.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Amoxicillin is a broad-spectrum penicillin active against a wide range of Gram-positive and Gram-negative bacteria. It works by blocking the bacteria's cell wall formation. Stable in stomach acid, it is absorbed quickly when taken by mouth, with peak blood levels reached within 1 to 2 hours of a dose. From there, it spreads widely through body tissues and fluids, though concentrations vary from one site to another.
Pregnancy & Breastfeeding
Amoxicillin falls under FDA pregnancy category B. That said, well-controlled studies in pregnant women are lacking, and since animal studies don't always predict how humans will respond, it's best used in pregnancy only when clearly needed. Amoxicillin does pass into breast milk, so it should be given to breastfeeding mothers with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.